Description

6-(Tetrahydro-2H-Pyran-2-Ylmethoxy)-Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Serves as a crucial building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing.
• Agrochemical Research: Used in the research and development of new generation pesticides and herbicides due to its pyridine-based scaffold.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	6-(Tetrahydro-2H-Pyran-2-Ylmethoxy)-Pyridine-2-Carboxylic Acid
CAS No.	1287217-35-9
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	6-((Tetrahydro-2H-pyran-2-yl)methoxy)picolinic acid; 6-(THP-O-Methoxy)picolinic acid; 2-Pyridinecarboxylic acid, 6-[(tetrahydro-2H-pyran-2-yl)methoxy]-; 6-(Tetrahydro-2H-pyran-2-ylmethoxy)pyridine-2-carboxylic acid; 6-(THPOM)-picolinic acid; Picolinic acid, 6-(tetrahydropyran-2-ylmethoxy)-; 1287217-35-9; 6-(THP-methoxy)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(Tetrahydro-2H-Pyran-2-Ylmethoxy)-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.