Description

6-(2-Chloro-4-Thiazol-5-Yl-Phenyl)-8-Ethyl-2-[4-(4-Methyl-Piperazin-1-Yl)-Phenylamino]-8H-Pyrido[2,3-D]Pyrimidin-7-One is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This molecule is of significant interest as a key synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor in medicinal chemistry. It is primarily targeted towards pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking novel scaffolds for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly in oncology and kinase inhibitor research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and target validation.
• Agrochemical Development: Investigated as a precursor for novel crop protection agents due to its complex heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	6-(2-Chloro-4-Thiazol-5-Yl-Phenyl)-8-Ethyl-2-[4-(4-Methyl-Piperazin-1-Yl)-Phenylamino]-8H-Pyrido[2,3-D]Pyrimidin-7-One
CAS No.	1286739-19-2
Molecular Formula	C29H26ClN7OS
Molecular Weight	556.08 g/mol
Synonyms	8H-Pyrido[2,3-d]pyrimidin-7-one, 6-[2-chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-; 6-(2-Chloro-4-(thiazol-5-yl)phenyl)-8-ethyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-8H-pyrido[2,3-d]pyrimidin-7-one; CAS 1286739-19-2; 1286739-19-2
EINECS	Contact for details

Quality Control

Our 6-(2-Chloro-4-Thiazol-5-Yl-Phenyl)-8-Ethyl-2-[4-(4-Methyl-Piperazin-1-Yl)-Phenylamino]-8H-Pyrido[2,3-D]Pyrimidin-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request. We support development projects requiring material meeting specific internal or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.