Description

Ethyl 2-Amino-3-(Methylcarbamoyl)-4,7-Dihydrothieno[2,3-C]Pyridine-6(5H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop next-generation drug candidates, leveraging its unique fused ring system to create molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing libraries of compounds in drug discovery programs targeting various disease pathways.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex heterocyclic compounds for academic and industrial research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of investigational and commercial drugs.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor modulators due to its specific structural features.

Basic Information

Product Name	Ethyl 2-Amino-3-(Methylcarbamoyl)-4,7-Dihydrothieno[2,3-C]Pyridine-6(5H)-Carboxylate
CAS No.	1286703-77-2
Molecular Formula	C12H17N3O3S
Molecular Weight	283.35 g/mol
Synonyms	Ethyl 2-Amino-3-(methylcarbamoyl)-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylate; 6-Carboxy-4,7-dihydro-5H-thieno[2,3-c]pyridine-3-carboxamide, 2-amino-, ethyl ester, N-methyl-; 2-Amino-N-methyl-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxamide ethyl ester (related form); Thienopyridine derivative intermediate; CAS 1286703-77-2
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-3-(Methylcarbamoyl)-4,7-Dihydrothieno[2,3-C]Pyridine-6(5H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.