Description

Spiro[Bicyclo[2.2.1]Heptane-7,1'-Cyclopropane]-5-Ene-2-Carboxylic Acid CAS NO 1286700-28-4 is a high-purity, complex spirocyclic carboxylic acid building block. This compound is valued for its unique three-dimensional structural framework, which is critical for modulating the physicochemical properties and biological activity of advanced molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

This specialized spirocyclic acid serves as a versatile intermediate in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and insecticides with unique modes of action.
• Material Science Research: Employed in the creation of advanced polymers and ligands with specific stereochemical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and asymmetric synthesis.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and optimization of synthetic routes for complex molecules.

Basic Information

Item	Details
Product Name	Spiro[Bicyclo[2.2.1]Heptane-7,1'-Cyclopropane]-5-Ene-2-Carboxylic Acid
CAS No.	1286700-28-4
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	5-Norbornene-2-spiro-1'-cyclopropane-2'-carboxylic Acid; Bicyclo[2.2.1]hept-5-ene-2-spiro-1'-cyclopropane-2'-carboxylic Acid; 2-Carboxyspiro[bicyclo[2.2.1]hept-5-ene-7,1'-cyclopropane]; Spiro[bicyclo[2.2.1]hept-5-ene-7,1'-cyclopropane]-2-carboxylic Acid; 5-Norbornene-2-spirocyclopropane-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Spiro[Bicyclo[2.2.1]Heptane-7,1'-Cyclopropane]-5-Ene-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch is analytically verified to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.