Description

Ethyl 6-Benzyl-2-Oxa-6-Azaspiro[3.4]Octane-8-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged spirocyclic structure.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or warhead design for targeted protein degradation molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	Ethyl 6-Benzyl-2-Oxa-6-Azaspiro[3.4]Octane-8-Carboxylate
CAS No.	1286692-89-4
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Ethyl 6-benzyl-2-oxa-6-azaspiro[3.4]octane-8-carboxylate; 8-Carbethoxy-6-benzyl-2-oxa-6-azaspiro[3.4]octane; 6-Benzyl-2-oxa-6-azaspiro[3.4]octane-8-carboxylic acid ethyl ester; 2-Oxa-6-azaspiro[3.4]octane-8-carboxylic acid, 6-benzyl-, ethyl ester; Ethyl 6-benzyl-2-oxa-6-azaspiro[3.4]octan-8-carboxylate; 1286692-89-4; 6-Benzyl-2-oxa-6-azaspiro[3.4]octane-8-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Benzyl-2-Oxa-6-Azaspiro[3.4]Octane-8-Carboxylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.