Description

L-Azidoleucine Cha Salt is a specialized, non-proteinogenic amino acid derivative featuring an azido functional group. This compound is of significant value as a key building block in chemical biology and pharmaceutical research, enabling bioorthogonal click chemistry for labeling and modifying biomolecules. It is primarily utilized by research scientists and process developers in the fields of proteomics, drug discovery, and the synthesis of novel peptide-based therapeutics and diagnostics.

Application

• Click Chemistry Reagent: Serves as a critical precursor for strain-promoted azide-alkyne cycloaddition (SPAAC) and copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate azido handles into peptide chains for subsequent conjugation.
• Bioconjugation & Labeling: Enables site-specific labeling of proteins, antibodies, and other biomolecules with fluorophores, biotin, or other functional tags.
• Chemical Biology Probes: A building block for creating activity-based probes to study enzyme function and protein-protein interactions.
• Pharmaceutical Intermediate: Employed in the research and development of novel peptide drugs and antibody-drug conjugates (ADCs).
• Material Science: Can be used to functionalize surfaces or polymers with bioactive peptides for tissue engineering or biosensor applications.

Basic Information

Product Name	L-Azidoleucine Cha Salt
CAS No.	1286670-79-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	L-2-Azido-4-methylpentanoic Acid Cyclohexylamine Salt; (2S)-2-Azido-4-methylpentanoic Acid Cyclohexylamine Salt; Azidoleucine-Cyclohexylamine Salt; N3-Leu-OH·Cha; Azido-Leucine Cha Salt; Leucine, 2-azido-, (2S)-, compd. with cyclohexanamine (1:1); Cha Salt of L-Azidoleucine
EINECS	Contact for details

Quality Control

Our L-Azidoleucine Cha Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥95.0%
Chiral Purity (HPLC)	≥98.0% (L-isomer)
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.