Description

4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core structure.
• Chemical Biology & Proteomics: Employed as a scaffold or probe in the study of protein-ligand interactions and enzyme function.
• Material Science Research: Investigated as a building block for advanced organic electronic materials due to its conjugated pyrido-pyrimidine system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Ethyl Ester
CAS No.	1286330-15-1
Molecular Formula	C11H9ClN3O2
Molecular Weight	250.66 g/mol
Synonyms	Ethyl 4-chloropyrido[3,4-d]pyrimidine-2-carboxylate; 4-Chloro-2-(ethoxycarbonyl)pyrido[3,4-d]pyrimidine; 4-Chloro-2-carbethoxy-pyrido[3,4-d]pyrimidine; Pyrido[3,4-d]pyrimidine-2-carboxylic acid, 4-chloro-, ethyl ester; 1286330-15-1; 4-Chloro-2-ethoxycarbonylpyrido[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.