Description

tert-Butyl 1-(4-Chlorobenzyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carbamate structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) with complex heterocyclic architectures.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 1-(4-Chlorobenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286275-72-6
Molecular Formula	C18H27ClN2O2
Molecular Weight	338.88 g/mol
Synonyms	1-(4-Chlorobenzyl)piperidin-4-amine, N-Boc derivative; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[(4-chlorophenyl)methyl]piperidine; tert-Butyl N-[1-[(4-chlorophenyl)methyl]-4-piperidyl]carbamate; 1-(4-Chlorobenzyl)-4-[(tert-butoxycarbonyl)amino]piperidine; BOC-1-(4-Chlorobenzyl)-4-aminopiperidine; 4-(Boc-amino)-1-(4-chlorobenzyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(4-Chlorobenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.