Description

Methyl 2-{[(4-tert-Butoxycarbonylamino)Piperidin-1-Yl]Methyl}Benzoate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold protected by a Boc (tert-butoxycarbonyl) group. This compound is crucial for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of therapeutic agents targeting the central nervous system, oncology, and other critical disease areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting neurological receptors and enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable piperidine and ester functional groups.
• API Synthesis: Serves as a critical building block in multi-step synthetic routes for complex active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.
• Academic Research: Used in university and institutional laboratories for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	Methyl 2-{[(4-tert-Butoxycarbonylamino)Piperidin-1-Yl]Methyl}Benzoate
CAS No.	1286274-53-0
Molecular Formula	C19H28N2O4
Molecular Weight	348.44 g/mol
Synonyms	1-(2-(Methoxycarbonyl)benzyl)-4-((tert-butoxycarbonyl)amino)piperidine; Methyl 2-((4-((tert-Butoxycarbonyl)amino)piperidin-1-yl)methyl)benzoate; 4-(Boc-amino)-1-(2-methoxycarbonylbenzyl)piperidine; 1-(2-Carbomethoxybenzyl)-4-N-Boc-aminopiperidine; 4-(tert-Butoxycarbonylamino)-1-(2-methoxycarbonylbenzyl)piperidine; Boc-4-Amino-1-(2-methoxycarbonylbenzyl)piperidine; CAS 1286274-53-0
EINECS	Contact for details

Quality Control

Our Methyl 2-{[(4-tert-Butoxycarbonylamino)Piperidin-1-Yl]Methyl}Benzoate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support both non-GMP and cGMP-grade requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.