Description

tert-Butyl 4-[(5-Nitropyridin-2-Yloxy)Methyl]Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry R&D: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for introducing functionalized piperidine and nitropyridine moieties into complex molecules.
• API Development: Employed in the pilot-scale and process development stages for new active pharmaceutical ingredients.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes for biological target identification and validation.

Basic Information

Product Name	tert-Butyl 4-[(5-Nitropyridin-2-Yloxy)Methyl]Piperidine-1-Carboxylate
CAS No.	1286274-42-7
Molecular Formula	C16H23N3O5
Molecular Weight	337.37 g/mol
Synonyms	1-Boc-4-[(5-Nitropyridin-2-yloxy)methyl]piperidine; 1-(tert-Butoxycarbonyl)-4-[(5-nitropyridin-2-yloxy)methyl]piperidine; tert-Butyl 4-((5-nitropyridin-2-yloxy)methyl)piperidine-1-carboxylate; 2-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methoxy)-5-nitropyridine; 4-[(5-Nitropyridin-2-Yloxy)Methyl]Piperidine-1-Carboxylic Acid tert-Butyl Ester; BOC-4-((5-Nitro-2-pyridyloxy)methyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(5-Nitropyridin-2-Yloxy)Methyl]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.