Description

tert-Butyl [(1-neopentylpiperidin-4-yl)methyl]carbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable piperidine and carbamate functionalities.
• Process Chemistry Development: Serves as a critical intermediate in scaling up the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Biology: Can be utilized as a probe or precursor in the development of chemical tools for biological target identification.

Basic Information

Product Name	tert-Butyl [(1-neopentylpiperidin-4-yl)methyl]carbamate
CAS No.	1286274-14-3
Molecular Formula	C16H32N2O2
Molecular Weight	284.44 g/mol
Synonyms	Boc-NH-CH2-1-Neopentylpiperidine; 1-Neopentyl-4-(Boc-aminomethyl)piperidine; tert-Butyl N-[(1-neopentyl-4-piperidyl)methyl]carbamate; 4-[(tert-Butoxycarbonylamino)methyl]-1-neopentylpiperidine; 1-(2,2-Dimethylpropyl)-4-[[(tert-butoxycarbonyl)amino]methyl]piperidine; N-Boc-1-Neopentyl-4-piperidinemethylamine; (1-Neopentylpiperidin-4-yl)methyl-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1-neopentylpiperidin-4-yl)methyl]carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.