Description

1-(2-Fluoro-5-Methoxybenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine core and substituted benzyl group. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery programs. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Biology Research: Used as a scaffold or precursor in the development of molecular probes and tool compounds for studying biological pathways.
• Medicinal Chemistry: Serves as a versatile synthon for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Preclinical Development: Utilized in the production of compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-(2-Fluoro-5-Methoxybenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1286274-06-3
Molecular Formula	C14H22Cl2FN3O
Molecular Weight	338.25 g/mol
Synonyms	4-Amino-1-[(2-fluoro-5-methoxyphenyl)methyl]piperidine dihydrochloride; 1-[(2-Fluoro-5-methoxyphenyl)methyl]-4-piperidinamine dihydrochloride; 1-(2-Fluoro-5-methoxybenzyl)piperidin-4-amine hydrochloride (1:2); 4-Amino-1-(2-fluoro-5-methoxybenzyl)piperidine dihydrochloride; 1-(2-Fluoro-5-methoxybenzyl)-4-aminopiperidine dihydrochloride; 1286274-06-3; 1-(2-Fluoro-5-methoxybenzyl)piperidin-4-amine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-Methoxybenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.