Description

tert-Butyl 4-(3-Aminopyridin-2-Yloxy)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with protected amine and pyridinyloxy functionalities. This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Kinase Inhibitor Synthesis: Used in the construction of heterocyclic scaffolds for potential kinase inhibitor libraries.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and target engagement.
• Peptidomimetic Chemistry: Incorporated into the design of peptidomimetics and conformationally constrained analogs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploration of new chemical space.

Basic Information

Product Name	tert-Butyl 4-(3-Aminopyridin-2-Yloxy)Piperidine-1-Carboxylate
CAS No.	1286272-96-5
Molecular Formula	C15H23N3O3
Molecular Weight	293.36 g/mol
Synonyms	1-Boc-4-[(3-amino-2-pyridinyl)oxy]piperidine; 1-(tert-Butoxycarbonyl)-4-[(3-amino-2-pyridinyl)oxy]piperidine; tert-Butyl 4-[(3-amino-2-pyridinyl)oxy]-1-piperidinecarboxylate; 4-(3-Aminopyridin-2-yloxy)piperidine-1-carboxylic acid tert-butyl ester; 2-[(1-Boc-4-piperidinyl)oxy]-3-aminopyridine; 3-Amino-2-(1-Boc-4-piperidyloxy)pyridine; BOC-4-(3-Amino-pyridin-2-yloxy)-piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Aminopyridin-2-Yloxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled in environments compatible with strong acids/organic solvents. Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.