Description

[1-(Pyridin-3-Ylmethyl)Piperidin-4-Yl]Methanamine Trihydrochloride is a high-purity, non-natural amino acid derivative and a key pharmaceutical intermediate. This compound is valued for its role as a sophisticated building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for neurological and oncological applications.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Ligand Synthesis: Serves as a precursor for creating complex ligands targeting specific receptors or enzymes.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) or other targeted drug delivery systems.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	[1-(Pyridin-3-Ylmethyl)Piperidin-4-Yl]Methanamine Trihydrochloride
CAS No.	1286264-46-7
Molecular Formula	C12H20Cl3N3
Molecular Weight	304.66 g/mol
Synonyms	1-[(Pyridin-3-yl)methyl]piperidin-4-ylmethanamine trihydrochloride; 4-(Aminomethyl)-1-(3-pyridinylmethyl)piperidine trihydrochloride; 1-(Pyridin-3-ylmethyl)piperidine-4-methanamine trihydrochloride; 1-(3-Pyridylmethyl)-4-piperidinemethanamine trihydrochloride; (1-((Pyridin-3-yl)methyl)piperidin-4-yl)methanamine trihydrochloride; 4-(Aminomethyl)-1-(pyridin-3-ylmethyl)piperidin-1-ium chloride hydrochloride
EINECS	Contact for details

Quality Control

Our [1-(Pyridin-3-Ylmethyl)Piperidin-4-Yl]Methanamine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.