Description

tert-Butyl [(1-Isonicotinoylpiperidin-4-Yl)Methyl]Carbamate is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex piperidine-based structures. Pharmaceutical R&D teams and fine chemical manufacturers need it to enable efficient, scalable synthesis pathways for new drug candidates, ensuring process reliability and high yield.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• API Development: Serves as a key precursor in the research and development of new Active Pharmaceutical Ingredients (APIs) with complex molecular architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of specialized compounds for clients.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and target validation.
• Process Chemistry: Applied in route scouting and process optimization for the scalable manufacturing of advanced intermediates.

Basic Information

Product Name	tert-Butyl [(1-Isonicotinoylpiperidin-4-Yl)Methyl]Carbamate
CAS No.	1286263-53-3
Molecular Formula	C17H25N3O3
Molecular Weight	319.40 g/mol
Synonyms	Boc-4-(Aminomethyl)-1-(isonicotinoyl)piperidine; 1-Boc-4-(Aminomethyl)-1-(4-pyridylcarbonyl)piperidine; tert-Butyl N-[[1-(pyridine-4-carbonyl)piperidin-4-yl]methyl]carbamate; 4-[[(tert-Butoxycarbonyl)amino]methyl]-1-(4-pyridinylcarbonyl)piperidine; 1-(Isonicotinoyl)-4-[(Boc-amino)methyl]piperidine; 1286263-53-3; Carbamic acid, N-[[1-(4-pyridinylcarbonyl)-4-piperidinyl]methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1-Isonicotinoylpiperidin-4-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.