Description

(R)-(3-Aminopyrrolidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride is a high-purity, chiral organic building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel therapeutic agents, particularly in the fields of neurology and oncology. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting G-protein coupled receptors (GPCRs).
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the development of new chemical entities (NCEs).
• Biochemical Research: Used as a ligand or precursor in the study of enzymatic processes and receptor binding assays.
• Asymmetric Synthesis: Employed as a building block requiring high enantiomeric purity for constructing complex molecular architectures.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Studies: Supplied for in vitro and in vivo pharmacological evaluation during early-stage drug discovery.

Basic Information

Item	Details
Product Name	(R)-(3-Aminopyrrolidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride
CAS No.	1286208-45-4
Molecular Formula	C10H14N3O•2HCl
Molecular Weight	277.16 g/mol (Free base: 192.24 g/mol)
Synonyms	(R)-1-(4-Pyridinylcarbonyl)-3-aminopyrrolidine dihydrochloride; (R)-N-(4-Pyridinyl)-3-aminopyrrolidine-1-carboxamide dihydrochloride; (R)-3-Amino-1-(pyridine-4-carbonyl)pyrrolidine dihydrochloride; (R)-3-Amino-1-(4-pyridinylcarbonyl)pyrrolidine hydrochloride (1:2); (R)-3-APC dihydrochloride; (R)-3-Aminopyrrolidine-1-(4-pyridine) ketone dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(3-Aminopyrrolidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.