Description

(S)-tert-Butyl 1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Ylcarbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound is specifically designed for the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemistry. It is a critical building block for research and production teams in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial precursor in the multi-step synthesis of target APIs where the (S)-pyrrolidine scaffold is required.
• Agrochemical Synthesis: Used in the research and development of advanced chiral pesticides and herbicides.
• Ligand and Catalyst Preparation: Acts as a starting material for the synthesis of chiral ligands used in asymmetric catalysis.
• Chemical Biology Research: Employed as a probe or building block in the study of biological pathways and receptor interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom production projects.

Basic Information

Product Name	(S)-tert-Butyl 1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Ylcarbamate
CAS No.	1286208-36-3
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	(S)-1-((Pyridin-4-yl)methyl)-N-(tert-butoxycarbonyl)pyrrolidin-3-amine; tert-Butyl (3S)-1-(4-pyridylmethyl)pyrrolidin-3-ylcarbamate; (S)-N-Boc-1-(4-Pyridylmethyl)-3-aminopyrrolidine; (S)-3-((tert-Butoxycarbonyl)amino)-1-(pyridin-4-ylmethyl)pyrrolidine; BOC-(S)-1-(4-Pyridylmethyl)-3-aminopyrrolidine; (S)-1-(Pyridin-4-ylmethyl)pyrrolidin-3-yl tert-butylcarbamate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.