Description

(S)-tert-Butyl 3-(3-Aminopyridin-2-Yloxy)Pyrrolidine-1-Carboxylate CAS NO 1286207-82-6 is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for kinase inhibitors and other small molecule therapeutics.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures containing both pyridine and pyrrolidine motifs.
• Research & Development (R&D): Serves as a critical reagent in academic and industrial laboratories for exploring new chemical entities and biological pathways.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for commercial API manufacturing.

Basic Information

Product Name	(S)-tert-Butyl 3-(3-Aminopyridin-2-Yloxy)Pyrrolidine-1-Carboxylate
CAS No.	1286207-82-6
Molecular Formula	C14H21N3O3
Molecular Weight	279.34 g/mol
Synonyms	1-Boc-3-((3-amino-2-pyridyl)oxy)-(S)-pyrrolidine; (S)-1-(tert-Butoxycarbonyl)-3-[(3-amino-2-pyridinyl)oxy]pyrrolidine; tert-Butyl (3S)-3-[(3-amino-2-pyridinyl)oxy]-1-pyrrolidinecarboxylate; (S)-tert-Butyl 3-((3-aminopyridin-2-yl)oxy)pyrrolidine-1-carboxylate; (S)-1-Boc-3-(3-aminopyridin-2-yloxy)pyrrolidine; (S)-3-(3-Amino-pyridin-2-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-(3-Aminopyridin-2-Yloxy)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with high-purity standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.