Description

(E)-3-(4-Isopropoxy-3-Methoxyphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its role as a key synthetic building block in the discovery of novel bioactive molecules, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule drug candidates.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Assays: Employed as a reference standard or test compound in high-throughput screening (HTS) and in vitro biological testing.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and organic synthesis.
• Custom Synthesis: A starting point for the custom manufacturing of specialized analogs and derivatives for client-specific projects.

Basic Information

Product Name	(E)-3-(4-Isopropoxy-3-Methoxyphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1285500-91-5
Molecular Formula	C20H21N5O3
Molecular Weight	379.42 g/mol
Synonyms	(E)-3-(4-Isopropoxy-3-methoxyphenyl)-N-(pyridin-3-ylmethylene)-1H-pyrazole-5-carbohydrazide; (E)-N-((Pyridin-3-yl)methylene)-3-(4-isopropoxy-3-methoxyphenyl)-1H-pyrazole-5-carbohydrazide; 3-(4-Isopropoxy-3-methoxyphenyl)-N-(pyridin-3-ylmethylidene)-1H-pyrazole-5-carbohydrazide; (E)-3-(4-Isopropoxy-3-methoxyphenyl)-N-(3-pyridylmethylene)-1H-pyrazole-5-carbohydrazide; CAS 1285500-91-5; Pyrazole carbohydrazide derivative
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Isopropoxy-3-Methoxyphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.