Description

3-Bromo-5-(4,4-Dimethylpiperidin-1-Ylsulfonyl)Pyridine is a high-value, multi-functional heterocyclic building block featuring a bromopyridine core and a sulfonamide-linked piperidine moiety. This compound is engineered to serve as a critical intermediate in advanced pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile bromine handle for cross-coupling reactions and the sulfonamide group for hydrogen bonding.
• Agrochemical Development: Intermediate in the creation of novel herbicides, fungicides, or insecticides that require specific heterocyclic architectures.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tools to study biological pathways and protein function.
• Material Science: Potential precursor for functionalized polymers or ligands used in catalysis and material synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Item	Details
Product Name	3-Bromo-5-(4,4-Dimethylpiperidin-1-Ylsulfonyl)Pyridine
CAS No.	1285282-44-1
Molecular Formula	C12H17BrN2O2S
Molecular Weight	333.25 g/mol
Synonyms	3-Bromo-5-[(4,4-dimethylpiperidin-1-yl)sulfonyl]pyridine; 5-Bromo-3-((4,4-dimethylpiperidin-1-yl)sulfonyl)pyridine; 1-(5-Bromopyridin-3-yl)sulfonyl-4,4-dimethylpiperidine; 3-Bromo-5-(4,4-dimethyl-1-piperidinylsulfonyl)pyridine; 1285282-44-1; 3-Bromo-5-(4,4-dimethylpiperidine-1-sulfonyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(4,4-Dimethylpiperidin-1-Ylsulfonyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.