Description

3-(3-Chloropiperidin-1-Ylsulfonyl)-5-Fluoropyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonyl-linked heterocyclic structure. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by R&D teams and process chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile sulfonamide and halogenated piperidine motifs.
• Agrochemical Synthesis: Intermediate in the development of new-generation pesticides and herbicides, leveraging its fluorine and chlorinated heterocycle.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds and probes to study biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic chemistry and novel methodology development.

Basic Information

Product Name	3-(3-Chloropiperidin-1-Ylsulfonyl)-5-Fluoropyridine
CAS No.	1283998-31-1
Molecular Formula	C10H12ClFN2O2S
Molecular Weight	278.73 g/mol
Synonyms	5-Fluoro-3-[(3-chloropiperidin-1-yl)sulfonyl]pyridine; 3-[(3-Chloropiperidin-1-yl)sulfonyl]-5-fluoropyridine; 1-(5-Fluoropyridin-3-yl)sulfonyl-3-chloropiperidine; 3-(3-Chloro-1-piperidinylsulfonyl)-5-fluoropyridine; 5-Fluoro-3-(3-chloropiperidine-1-sulfonyl)pyridine; 1283998-31-1; 3-(3-Chloropiperidin-1-ylsulfonyl)-5-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chloropiperidin-1-Ylsulfonyl)-5-Fluoropyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to support its use in regulated research environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation (NMR, MS), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids/bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.