Description

Piperidine, 4-(Difluoromethyl)-, Hydrochloride (1:1) is a high-purity, specialty organic building block designed for advanced chemical synthesis. This compound is valued for its unique difluoromethyl-substituted piperidine core, which is critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluoromethyl group can enhance biological activity and environmental stability.
• Chemical Synthesis Reagent: Serves as a versatile precursor for introducing the 4-(difluoromethyl)piperidine moiety into more complex molecular architectures.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or as a structural component in organocatalysts.
• Material Science Research: Potential use in the synthesis of advanced organic materials and functional polymers.

Basic Information

Product Name	Piperidine, 4-(Difluoromethyl)-, Hydrochloride (1:1)
CAS No.	1283717-58-7
Molecular Formula	C6H12ClF2N
Molecular Weight	171.62 g/mol
Synonyms	4-(Difluoromethyl)piperidine hydrochloride; 4-(Difluoromethyl)piperidine HCl; 1-(Difluoromethyl)-4-piperidinol hydrochloride (tautomer); 4-Piperidinemethanol, α,α-difluoro-, hydrochloride; Piperidine-4-carbinol, difluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our Piperidine, 4-(Difluoromethyl)-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.