Description

1-Benzyl-6-Chloro-7-Fluoro-1H-Spiro[Furo[3,4-C]Pyridine-3,4-Piperidin]-1-One is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and fused heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents, especially within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• API Development: Serves as a critical precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs), particularly for potential CNS and oncology therapeutics.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and process development projects.
• Biochemical Tool Compound: Potential use as a probe or reference standard in biochemical and pharmacological assays to study specific biological targets.

Basic Information

Product Name	1-Benzyl-6-Chloro-7-Fluoro-1H-Spiro[Furo[3,4-C]Pyridine-3,4-Piperidin]-1-One
CAS No.	1283090-74-3
Molecular Formula	C19H16ClFN2O2
Molecular Weight	358.80 g/mol
Synonyms	1-Benzyl-6-chloro-7-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one; 1H-Spiro[furo[3,4-c]pyridine-3,4'-piperidine]-1-one, 1-benzyl-6-chloro-7-fluoro-; 1283090-74-3; 6-Chloro-7-fluoro-1-benzylspiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one; Spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one, 1-benzyl-6-chloro-7-fluoro-
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Chloro-7-Fluoro-1H-Spiro[Furo[3,4-C]Pyridine-3,4-Piperidin]-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.