Description

1-(5-Bromopyridin-3-Ylsulfonyl)Azepane is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and azepane sulfonamide scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Protease Inhibitor Development: The sulfonamide moiety makes it a valuable scaffold for designing enzyme inhibitors.
• Kinase Inhibitor Synthesis: Employed in the construction of molecules targeting kinase enzymes relevant in cancer and inflammatory diseases.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Azepane
CAS No.	1282261-07-7
Molecular Formula	C11H15BrN2O2S
Molecular Weight	319.22 g/mol
Synonyms	Azepane, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1-[(5-Bromopyridin-3-yl)sulfonyl]azepane; 5-Bromo-3-(azepane-1-sulfonyl)pyridine; 3-(Azepane-1-sulfonyl)-5-bromopyridine; 1-(5-Bromo-3-pyridinesulfonyl)azepane; 1-(5-Bromopyridin-3-ylsulfonyl)azepane
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Azepane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.