Description

2,6-Diazaspiro[3.5]Nonane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) is a high-purity, protected spirocyclic diamine building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel therapeutic agents. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery programs targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry.
• Protease Inhibitor Scaffold: Used in the research and development of protease inhibitor drugs due to its spirocyclic diamine structure.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design of peptidomimetics to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and biological pathways.
• Library Synthesis for HTS: A valuable reactant for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.

Basic Information

Product Name	2,6-Diazaspiro[3.5]Nonane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1)
CAS No.	1279844-25-5
Molecular Formula	C12H23ClN2O2
Molecular Weight	262.78 g/mol
Synonyms	tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate hydrochloride; 2,6-Diazaspiro[3.5]nonane-6-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride; 6-Boc-2,6-diazaspiro[3.5]nonane hydrochloride; Boc-2,6-diazaspiro[3.5]nonane HCl; 2,6-Diazaspiro[3.5]nonane-6-carboxylic acid tert-butyl ester hydrochloride; 6-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.5]nonane hydrochloride
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.5]Nonane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.