Description

tert-Butyl 2-(6-Chloropyridin-2-Yl)-2-Cyanoacetate is a high-value, multifunctional chemical intermediate featuring a pyridine core substituted with chloro and cyanoacetate ester groups. This compound is critical for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides, leveraging the bioactivity of the pyridine-chloro moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	tert-Butyl 2-(6-Chloropyridin-2-Yl)-2-Cyanoacetate
CAS No.	1279818-57-3
Molecular Formula	C₁₂H₁₃ClN₂O₂
Molecular Weight	252.70 g/mol
Synonyms	2-(6-Chloro-2-pyridinyl)-2-cyanoacetic acid 1,1-dimethylethyl ester; tert-Butyl (6-chloropyridin-2-yl)(cyano)acetate; 2-Cyano-2-(6-chloropyridin-2-yl)acetic acid tert-butyl ester; 6-Chloro-2-pyridylcyanoacetic acid tert-butyl ester; t-Butyl 2-cyano-2-(6-chloropyridin-2-yl)acetate; (6-Chloro-2-pyridyl)(cyano)acetic acid tert-butyl ester; 1279818-57-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(6-Chloropyridin-2-Yl)-2-Cyanoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.