Description

n-Azidoacetylglucosamine is a chemically modified monosaccharide derivative, specifically an azido-functionalized analog of N-acetylglucosamine. This compound is a crucial building block in chemical biology and glycochemistry, enabling the site-specific labeling and study of glycans via bioorthogonal click chemistry reactions. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and diagnostic reagent production who require tools for metabolic glycan engineering and glycoprotein analysis.

Application

• Metabolic Glycan Engineering: Incorporated into cellular glycans as a bioorthogonal chemical reporter for subsequent labeling with alkyne-bearing probes via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Glycoprotein and Proteomics Research: Used as a tool compound to label and visualize newly synthesized O-GlcNAc-modified proteins in live cells and tissues.
• Drug Discovery & Development: Serves as a precursor for synthesizing more complex azido-sugar probes or for developing carbohydrate-based vaccines and therapeutics.
• Diagnostic Reagent Manufacturing: Employed in the production of labeled substrates and standards for enzymatic assays targeting glycosyltransferases or glycosidases.
• Bioconjugation and Material Science: Facilitates the functionalization of surfaces, nanoparticles, or polymers with sugar moieties for biosensor and biomaterial applications.
• Academic & Industrial R&D: A key reagent for fundamental research in glycoscience, chemical biology, and cell surface engineering.

Basic Information

Item	Details
Product Name	n-Azidoacetylglucosamine
CAS No.	1279573-92-0
Molecular Formula	C8H14N4O6
Molecular Weight	262.22 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-β-D-glucopyranose; 2-Azido-2-deoxy-D-glucose pentaacetate; 2-Azido-2-deoxyglucose tetraacetate; GlcNAz; N-Azidoacetyl-D-glucosamine; Azido-modified N-acetylglucosamine; Peracetylated GlcNAz; Ac4GlcNAz
EINECS	Contact for details

Quality Control

Our n-Azidoacetylglucosamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under inert atmosphere or with desiccant after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.