Description

2-Amino-1-(4-Chloropyridin-2-Yl)Ethanone is a high-purity, synthetically valuable organic intermediate featuring a reactive amino ketone functional group attached to a chloropyridine scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the bioactivity of the chloropyridine moiety.
• Chemical Research & Development: Serves as a versatile precursor for constructing complex heterocyclic frameworks in academic and industrial labs.
• Ligand and Catalyst Development: The amino and ketone groups make it a useful starting material for synthesizing specialized ligands for metal catalysis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and photoactive compounds.

Basic Information

Item	Detail
Product Name	2-Amino-1-(4-Chloropyridin-2-Yl)Ethanone
CAS No.	1278596-14-7
Molecular Formula	C7H7ClN2O
Molecular Weight	170.60 g/mol
Synonyms	1-(4-Chloro-2-pyridinyl)-2-aminoethanone; 2-Amino-1-(4-chloro-2-pyridinyl)ethanone; 2-Acetamido-4-chloropyridine (tautomer); 4-Chloro-2-(2-aminoacetyl)pyridine; Ethanone, 2-amino-1-(4-chloro-2-pyridinyl)-; 4-Chloropyridin-2-yl amino ketone
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4-Chloropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.