Description

3-Bromo-5-(3-Fluorophenyl)-Pyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to form biaryl structures.
• Ligand Synthesis: Utilized in the preparation of sophisticated nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a versatile scaffold for labeling and probe development in biochemical and diagnostic research.

Basic Information

Product Name	3-Bromo-5-(3-Fluorophenyl)-Pyridine
CAS No.	1276123-21-7
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	3-Bromo-5-(3-fluorophenyl)pyridine; 5-(3-Fluorophenyl)-3-bromopyridine; 3-Bromo-5-(m-fluorophenyl)pyridine; 3-Bromo-5-(3-fluoro-phenyl)-pyridine; (3-Fluorophenyl)-5-bromopyridine; 3-Bromo-5-(3-fluorophenyl)pyridine, 1276123-21-7; 3-Bromo-5-(3'-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(3-Fluorophenyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.