Description

3-Bromo-5-(4-Chloropiperidin-1-Ylsulfonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonyl-linked heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted small-molecule libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile bromo and sulfonyl functional groups.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides or fungicides with potential new modes of action.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for investigating biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	3-Bromo-5-(4-Chloropiperidin-1-Ylsulfonyl)Pyridine
CAS No.	1275947-60-8
Molecular Formula	C10H12BrClN2O2S
Molecular Weight	339.64 g/mol
Synonyms	3-Bromo-5-[(4-chloropiperidin-1-yl)sulfonyl]pyridine; 3-Bromo-5-(4-chloro-1-piperidinyl)sulfonylpyridine; Pyridine, 3-bromo-5-[(4-chloro-1-piperidinyl)sulfonyl]-; 1275947-60-8
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(4-Chloropiperidin-1-Ylsulfonyl)Pyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.