Description

(1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide-linked pyrrolidine-pyridine hybrid structure. This compound matters for its critical role as a sophisticated building block in modern medicinal chemistry, enabling the synthesis of targeted bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Its structural motifs are valuable for designing potential inhibitors targeting specific protein kinases involved in disease pathways.
• Bioconjugation & Probe Synthesis: The functional groups allow for use in creating chemical probes for biochemical and diagnostic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Yl)Methanol
CAS No.	1275700-61-2
Molecular Formula	C10H13BrN2O3S
Molecular Weight	321.19 g/mol
Synonyms	3-(Hydroxymethyl)-1-[(5-bromo-3-pyridinyl)sulfonyl]pyrrolidine; 1-[(5-Bromopyridin-3-yl)sulfonyl]pyrrolidin-3-ylmethanol; (1-((5-Bromopyridin-3-yl)sulfonyl)pyrrolidin-3-yl)methanol; Pyrrolidin-3-ylmethanol, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1275700-61-2
EINECS	Contact for details

Quality Control

Our (1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.