Description

cis-tert-Butyl4-Oxohexahydro-1H-Pyrrolo[3,4-C]Pyridine-2(3H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, fused bicyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and novel APIs.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for candidate drugs during preclinical and clinical development phases.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	cis-tert-Butyl4-Oxohexahydro-1H-Pyrrolo[3,4-C]Pyridine-2(3H)-Carboxylate
CAS No.	1273568-51-6
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	tert-Butyl cis-4-oxohexahydro-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxylate; (3aR,7aS)-tert-Butyl 4-oxohexahydro-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxylate; cis-2-(tert-Butoxycarbonyl)-2,3,3a,4,7,7a-hexahydro-1H-pyrrolo[3,4-c]pyridin-4-one; BOC-protected pyrrolopyridinone; 1273568-51-6; tert-Butyl 4-oxo-1,3,3a,4,7,7a-hexahydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate (cis)
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl4-Oxohexahydro-1H-Pyrrolo[3,4-C]Pyridine-2(3H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.