Description

6-Bromo-5-Hydroxy-Pyridine-2-Carbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique bromo-hydroxy-aldehyde substitution pattern makes it an invaluable intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific molecular complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogen and aldehyde functionality for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functional organic materials, such as conductive polymers, metal-organic frameworks (MOFs), and organic light-emitting diodes (OLED) precursors.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to its reactive aldehyde group for bioconjugation.

Basic Information

Product Name	6-Bromo-5-Hydroxy-Pyridine-2-Carbaldehyde
CAS No.	1273422-87-9
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	5-Hydroxy-6-bromopyridine-2-carboxaldehyde; 2-Bromo-3-hydroxy-6-formylpyridine; 6-Bromo-5-hydroxypicolinaldehyde; 6-Bromo-5-hydroxy-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 6-bromo-5-hydroxy-; 6-Bromo-5-hydroxypyridine-2-carbaldehyde; 5-Hydroxy-6-bromo-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-5-Hydroxy-Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.