Description

Ethyl 2-Amino-5-Fluoro-2,3-Dihydro-1H-Indene-2-Carboxylate Hcl CAS NO 1272758-28-7 is a high-purity, fluorinated indane derivative used as a critical pharmaceutical intermediate. This compound is valued for its role in constructing complex molecular scaffolds, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated indane structure.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and fine chemicals.
• Academic & R&D: Employed in university and corporate research laboratories for medicinal chemistry and methodological studies.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of specialty chemicals.

Basic Information

Product Name	Ethyl 2-Amino-5-Fluoro-2,3-Dihydro-1H-Indene-2-Carboxylate Hydrochloride
CAS No.	1272758-28-7
Molecular Formula	C₁₂H₁₅ClFNO₂
Molecular Weight	259.70 g/mol
Synonyms	2-Amino-5-fluoro-2,3-dihydro-1H-indene-2-carboxylic acid ethyl ester hydrochloride; Ethyl 2-amino-5-fluoroindane-2-carboxylate HCl; 5-Fluoro-2,3-dihydro-1H-indene-2-carboxylic acid, 2-amino-, ethyl ester, hydrochloride; 1272758-28-7; Ethyl 2-Amino-5-Fluoro-2,3-Dihydro-1H-Indene-2-Carboxylate Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-5-Fluoro-2,3-Dihydro-1H-Indene-2-Carboxylate Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.