Description

3,4-Dihydro-1H-Spiro[Naphthalene-2,4-Piperidine] Hcl is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients, particularly those with spirocyclic architectures.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex organic molecules in custom synthesis and contract manufacturing.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and enzyme interactions in academic and industrial research.

Basic Information

Product Name	3,4-Dihydro-1H-Spiro[Naphthalene-2,4-Piperidine] Hydrochloride
CAS No.	1272758-22-1
Molecular Formula	C₁₄H₁₉N•HCl
Molecular Weight	237.77 g/mol
Synonyms	1'H-Spiro[naphthalene-2,4'-piperidine], 3,4-dihydro-, hydrochloride; 3,4-Dihydro-1H-spiro[naphthalene-2,4'-piperidine] hydrochloride; Spiro[naphthalene-2,4'-piperidine], 3,4-dihydro-, hydrochloride; 1272758-22-1; 3,4-Dihydro-1H-spiro(naphthalene-2,4'-piperidine) HCl; 1'H-Spiro(naphthalene-2,4'-piperidine), 3,4-dihydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1H-Spiro[Naphthalene-2,4-Piperidine] Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.