Description

Ethyl 4-Oxospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic quinazoline scaffold. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially those targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct sophisticated heterocyclic systems.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Ethyl 4-Oxospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-5-Carboxylate
CAS No.	1272756-22-5
Molecular Formula	C16H20N2O3
Molecular Weight	288.34 g/mol
Synonyms	Ethyl 5-carboxy-4-oxospiro[1,2,3,4-tetrahydroquinazoline-2,1'-cyclopentane]carboxylate; 5-Carbethoxy-4-oxospiro[1,2,3,4-tetrahydroquinazoline-2,1'-cyclopentane]; Spiro[cyclopentane-1,2'-[1,2,3,4]tetrahydroquinazoline]-4-one, 5-carboxylic acid ethyl ester; Ethyl 4-oxo-1,2,3,4-tetrahydrospiro[quinazoline-2,1'-cyclopentane]-5-carboxylate; 1272756-22-5
EINECS	Contact for details

Quality Control

Our Ethyl 4-Oxospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and NMR, are validated to provide reliable specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.