Description

6-Bromospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-4-One is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic quinazolinone scaffold. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of novel drug candidates with potential activity against a range of therapeutic targets. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the development of new small-molecule therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of chemical probes to study biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Bromospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-4-One
CAS No.	1272756-17-8
Molecular Formula	C₁₃H₁₃BrN₂O
Molecular Weight	293.16 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydrospiro[quinazoline-2,1'-cyclopentane]-4-one; 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1'-cyclopentane]-4(1H)-one; 6-Bromo-1,2,3,4-tetrahydro-4-oxospiro[quinazoline-2,1'-cyclopentane]; Spiro[cyclopentane-1,2'-[1,2,3,4]tetrahydroquinazolin]-4'-one, 6'-bromo-; 1272756-17-8; 6-Bromo-spiro-tetrahydroquinazolinone.
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[1,2,3,4-Tetrahydroquinazoline-2,1'-Cyclopentane]-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.