Description

7-(3-Nitrophenyl)-5,8-Diazaspiro[3.4]Octan-6-One is a high-value, nitrogen-containing spirocyclic compound featuring a nitrophenyl substituent, making it a sophisticated building block for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its unique diazaspiro[3.4]octane scaffold is leveraged to modulate molecular properties and biological activity. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Agrochemical Synthesis: Employed in the development of novel herbicides or insecticides, where the spirocyclic structure can contribute to new modes of action.
• Chemical Biology Probe Development: Acts as a core structure for designing molecular probes to study enzyme function or protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from milligram to kilogram.

Basic Information

Product Name	7-(3-Nitrophenyl)-5,8-Diazaspiro[3.4]Octan-6-One
CAS No.	1272755-97-1
Molecular Formula	C12H11N3O3
Molecular Weight	245.24 g/mol
Synonyms	7-(3-Nitrophenyl)-5,8-diazaspiro[3.4]octan-6-one; 5,8-Diazaspiro[3.4]octan-6-one, 7-(3-nitrophenyl)-; 7-(3-Nitrophenyl)-5,8-diazaspiro[3.4]octane-6-one; 1272755-97-1; 3-Nitrophenyl diazaspirooctanone; Spirocyclic nitrophenyl lactam
EINECS	Contact for details

Quality Control

Our 7-(3-Nitrophenyl)-5,8-Diazaspiro[3.4]Octan-6-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.