Description

3-(2-Bromophenyl)-1,4-Diazaspiro[4.4]Nonan-2-One is a high-value, spirocyclic organic building block featuring a brominated aromatic ring, which provides a versatile handle for further synthetic elaboration. This compound is critical for medicinal chemistry research and the development of novel pharmaceutical candidates, particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily sought after by R&D chemists and process development scientists in pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize biological activity.
• Agrochemical Development: Employed in the research phase for creating novel active ingredients with specific modes of action.
• Ligand and Catalyst Synthesis: Acts as a scaffold for developing novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function or protein-protein interactions.
• Advanced Material Precursor: Potential building block for organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(2-Bromophenyl)-1,4-Diazaspiro[4.4]Nonan-2-One
CAS No.	1272755-96-0
Molecular Formula	C14H15BrN2O
Molecular Weight	307.19 g/mol
Synonyms	3-(2-Bromophenyl)-1,4-diazaspiro[4.4]nonan-2-one; 1,4-Diazaspiro[4.4]nonan-2-one, 3-(2-bromophenyl)-; 2-Bromophenyl diazaspiro nonanone; Spirocyclic bromophenyl lactam; 3-(o-Bromophenyl)-1,4-diazaspiro[4.4]nonan-2-one; BRN 25123017; SCHEMBL21808531
EINECS	Contact for details

Quality Control

Our 3-(2-Bromophenyl)-1,4-Diazaspiro[4.4]Nonan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.