Description

2-(3-Oxo-1,4-diazaspiro[4.4]non-2-yl)benzonitrile is a high-value, spirocyclic organic compound featuring a benzonitrile moiety fused to a diazaspiro[4.4]nonane core, making it a sophisticated building block for advanced chemical synthesis. Its unique heterocyclic architecture is critical for developing novel pharmacologically active molecules, particularly in medicinal chemistry and drug discovery. This intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries seeking to create new active ingredients with targeted properties.

Application

The spirocyclic structure of this compound makes it a versatile intermediate for synthesizing complex molecules. Its primary applications include:

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to improve potency and selectivity of potential therapeutics.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides with new modes of action.
• Chemical Biology: Employed as a probe or scaffold in the development of chemical tools for studying biological pathways and protein interactions.
• Advanced Material Synthesis: Potential use as a monomer or precursor for creating specialty polymers and functional materials with specific electronic or optical properties.

Basic Information

Product Name	2-(3-Oxo-1,4-diazaspiro[4.4]non-2-yl)benzonitrile
CAS No.	1272755-94-8
Molecular Formula	C14H13N3O
Molecular Weight	239.27 g/mol
Synonyms	2-(3-Oxo-1,4-diazaspiro[4.4]nonan-2-yl)benzonitrile; Benzonitrile, 2-(3-oxo-1,4-diazaspiro[4.4]non-2-yl)-; 1,4-Diazaspiro[4.4]nonan-3-one, 2-(2-cyanophenyl)-; 2-(2-Cyanophenyl)-1,4-diazaspiro[4.4]nonan-3-one; 1272755-94-8; Spirocyclic benzonitrile derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of customers operating under cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.