Description

2-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic cores for potential kinase inhibitors due to its diazaspiro structure.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile
CAS No.	1272755-93-7
Molecular Formula	C13H11N3O
Molecular Weight	225.25 g/mol
Synonyms	2-(7-Oxo-5,8-diazaspiro[3.4]octan-6-yl)benzonitrile; 6-(2-Cyanophenyl)-5,8-diazaspiro[3.4]octan-7-one; Benzonitrile, 2-(7-oxo-5,8-diazaspiro[3.4]oct-6-yl)-; 1272755-93-7; 2-(7-Oxo-5,8-diazaspiro[3.4]oct-6-yl)benzonitrile; 6-(2-Cyanophenyl)-5,8-diazaspiro[3.4]octan-7-one; Spiro[diazacyclopentane-5,1'-cyclopropane] intermediate
EINECS	Contact for details

Quality Control

Our 2-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.