Description

7-(5-Bromo-2-Fluorophenyl)-5,8-Diazaspiro[3.4]Octan-6-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at R&D teams and process chemists in the pharmaceutical and biotechnology industries engaged in drug discovery programs, particularly those focused on central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
• Kinase Inhibitor Synthesis: Employed in the construction of novel kinase inhibitor candidates due to its privileged heterocyclic structure.
• Chemical Biology Probes: Utilized for creating specialized molecular probes to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring high-fidelity, complex heterocyclic building blocks.

Basic Information

Product Name	7-(5-Bromo-2-Fluorophenyl)-5,8-Diazaspiro[3.4]Octan-6-One
CAS No.	1272755-91-5
Molecular Formula	C12H11BrFN2O
Molecular Weight	313.14 g/mol
Synonyms	5,8-Diazaspiro[3.4]octan-6-one, 7-(5-bromo-2-fluorophenyl)-; 7-(5-Bromo-2-fluorophenyl)-5,8-diazaspiro[3.4]octan-6-one; 1272755-91-5; 5,8-Diazaspiro[3.4]octane-6-one, 7-(5-bromo-2-fluorophenyl)-; Spiro[3.4]octane-6-one, 7-(5-bromo-2-fluorophenyl)-5,8-diaza-; AKOS026714249; F2198-1560; BCP34043
EINECS	Contact for details

Quality Control

Our 7-(5-Bromo-2-Fluorophenyl)-5,8-Diazaspiro[3.4]Octan-6-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with the standards required for cGMP and non-GMP research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.