Description

Methyl 2-(5-Bromopyridin-3-Ylsulfonyl)Acetate CAS NO 1272357-08-0 is a high-purity, specialized organic building block featuring a bromopyridine core and a sulfonylacetate ester functional group. This compound is critically important for its role as a versatile intermediate in advanced pharmaceutical synthesis and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging the bioactive bromopyridine moiety.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom chemical synthesis services catering to diverse R&D needs.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and sulfone chemistry.

Basic Information

Product Name	Methyl 2-(5-Bromopyridin-3-Ylsulfonyl)Acetate
CAS No.	1272357-08-0
Molecular Formula	C8H8BrNO4S
Molecular Weight	294.12 g/mol
Synonyms	Methyl (5-Bromo-3-pyridylsulfonyl)acetate; Acetic acid, 2-[(5-bromo-3-pyridinyl)sulfonyl]-, methyl ester; 3-Pyridinesulfonylacetic acid, 5-bromo-, methyl ester; Methyl 2-((5-bromopyridin-3-yl)sulfonyl)acetate; 1272357-08-0; Methyl 5-bromopyridine-3-sulfonylacetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Bromopyridin-3-Ylsulfonyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.