Description

1-(5-Bromo-3-Fluoro-2-Pyridyl)Ethylamine CAS NO 1270491-25-2 is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which provides reactive handles for cross-coupling and further functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Item	Detail
Product Name	1-(5-Bromo-3-Fluoro-2-Pyridyl)Ethylamine
CAS No.	1270491-25-2
Molecular Formula	C7H8BrFN2
Molecular Weight	219.06 g/mol
Synonyms	1-(5-Bromo-3-fluoropyridin-2-yl)ethan-1-amine; 1-(5-Bromo-3-fluoro-2-pyridinyl)ethylamine; 2-Pyridineethanamine, 5-bromo-3-fluoro-; 5-Bromo-3-fluoro-2-(1-aminoethyl)pyridine; α-Aminoethyl-5-bromo-3-fluoropyridine; 1-Aminoethyl-5-bromo-3-fluoropyridine; Ethanamine, 1-(5-bromo-3-fluoro-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Fluoro-2-Pyridyl)Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.