Description

1-(3,5-Difluoropyridin-4-Yl)Ethan-1-Amine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the creation of novel pharmacophores with enhanced metabolic stability and binding affinity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoropyridine moiety can improve biological activity and environmental profile.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen-containing heterocyclic structure.
• Material Science Research: Acts as a precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(3,5-Difluoropyridin-4-Yl)Ethan-1-Amine
CAS No.	1270488-52-2
Molecular Formula	C7H8F2N2
Molecular Weight	158.15 g/mol
Synonyms	1-(3,5-Difluoropyridin-4-yl)ethanamine; 1-(3,5-Difluoro-4-pyridinyl)ethanamine; 4-Pyridineethanamine, 3,5-difluoro-; 1-(3,5-Difluoropyridin-4-yl)ethylamine; Ethan-1-amine, 1-(3,5-difluoropyridin-4-yl)-; 3,5-Difluoro-4-(1-aminoethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluoropyridin-4-Yl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.