Description

α-Methylimidazo[1,2-A]Pyridine-6-Methanamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where consistent quality and reliable supply are critical.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules, especially in medicinal chemistry research and development.
• API Synthesis: Used as a core scaffold for constructing novel Active Pharmaceutical Ingredients (APIs) with potential neurological or psychiatric applications.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex nitrogen-containing heterocycles due to its reactive amine and imidazopyridine functionalities.
• Chemical Research & Development: Essential for process chemistry development, route scouting, and scale-up activities for new chemical entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial drug substances under GMP guidelines.

Basic Information

Product Name	α-Methylimidazo[1,2-A]Pyridine-6-Methanamine
CAS No.	1270475-03-0
Molecular Formula	C9H11N3
Molecular Weight	161.21 g/mol
Synonyms	6-(Aminomethyl)-2-methylimidazo[1,2-a]pyridine; 2-Methylimidazo[1,2-a]pyridine-6-methanamine; 6-(Aminomethyl)-2-methylimidazo[1,2-a]pyridine; 2-Methyl-6-(aminomethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-methanamine, 2-methyl-; (6-Methylimidazo[1,2-a]pyridin-2-yl)methanamine; α-Methylimidazo[1,2-A]Pyridine-6-Methylamine
EINECS	Contact for details

Quality Control

Our α-Methylimidazo[1,2-A]Pyridine-6-Methanamine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.