Description

1-(6-Chloropyridin-3-Yl)-1-Cyclopropylmethanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique chloropyridine and cyclopropylamine scaffold. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical research sectors. It is primarily sought after by R&D chemists and process development scientists working on innovative crop protection agents and therapeutic candidates.

Application

• Key Intermediate in Agrochemical Synthesis: Serves as a critical building block for the development of next-generation insecticides and pesticides, leveraging the bioactivity of the chloropyridine moiety.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the construction of novel heterocyclic compounds with potential therapeutic applications.
• Ligand and Catalyst Preparation: The amine functional group makes it a suitable precursor for creating specialized ligands used in catalytic processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of tailored molecules for client projects.

Basic Information

Item	Detail
Product Name	1-(6-Chloropyridin-3-Yl)-1-Cyclopropylmethanamine
CAS No.	1270394-92-7
Molecular Formula	C9H11ClN2
Molecular Weight	182.65 g/mol
Synonyms	1-(6-Chloro-3-pyridinyl)-1-cyclopropanemethanamine; 1-(6-Chloropyridin-3-yl)-1-cyclopropylmethanamine; 1-Cyclopropyl-1-(6-chloropyridin-3-yl)methanamine; 6-Chloro-3-(1-cyclopropylaminomethyl)pyridine; (6-Chloropyridin-3-yl)(cyclopropyl)methanamine; CPMA (abbreviation); α-Cyclopropylamino-6-chloronicotinonitrile precursor
EINECS	Contact for details

Quality Control

Every batch of 1-(6-Chloropyridin-3-Yl)-1-Cyclopropylmethanamine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.