Description

2-Chloro-5-Fluoro-3-(Pyrrolidin-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a halogenated pyridine core fused with a pyrrolidine moiety, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients. Its utility extends to material science for the development of specialty chemicals and functional ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Employed to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-(Pyrrolidin-2-Yl)Pyridine
CAS No.	1270360-19-4
Molecular Formula	C9H10ClFN2
Molecular Weight	200.64 g/mol
Synonyms	2-Chloro-5-fluoro-3-(2-pyrrolidinyl)pyridine; 3-(Pyrrolidin-2-yl)-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-3-pyrrolidin-2-ylpyridine; 1270360-19-4; 2-Chloro-5-fluoro-3-(2-pyrrolidinyl)pyridine; Pyridine, 2-chloro-5-fluoro-3-(2-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-3-(Pyrrolidin-2-Yl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.