Description

Thiazolo[4,5-C]Pyridine-5(4H)-Carboxylic Acid, 6,7-Dihydro-2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester is a high-value, heterocyclic organic building block featuring a fused thiazole and pyridine core with a protected carboxylic acid group. This compound is of significant interest for its role as a sophisticated synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its unique fused heterocyclic scaffold.
• Agrochemical Synthesis: Intermediate in the development of new-generation herbicides and fungicides with complex heterocyclic structures.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and enzyme functions.
• Material Science Research: Potential precursor for specialty chemicals and advanced organic materials requiring specific electronic properties.

Basic Information

Product Name	Thiazolo[4,5-C]Pyridine-5(4H)-Carboxylic Acid, 6,7-Dihydro-2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1269532-60-6
Molecular Formula	C13H17NO3S
Molecular Weight	267.34 g/mol
Synonyms	tert-Butyl 6,7-dihydro-2-(hydroxymethyl)thiazolo[4,5-c]pyridine-5(4H)-carboxylate; 1,1-Dimethylethyl 6,7-dihydro-2-(hydroxymethyl)-4H-thiazolo[4,5-c]pyridine-5-carboxylate; 1269532-60-6; Thiazolo[4,5-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-(hydroxymethyl)-, 1,1-dimethylethyl ester; tert-Butyl 2-(hydroxymethyl)-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.