Description

tert-Butyl 4-(5-Bromo-3-Cyanopyridin-2-Yl)Piperazine-1-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical discovery, offering a versatile scaffold for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services and contract research organizations (CROs/CMOs) producing specialized compounds.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 4-(5-Bromo-3-Cyanopyridin-2-Yl)Piperazine-1-Carboxylate
CAS No.	1269492-47-8
Molecular Formula	C15H19BrN4O2
Molecular Weight	367.25 g/mol
Synonyms	1-Boc-4-(5-Bromo-3-cyano-2-pyridyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(5-bromo-3-cyanopyridin-2-yl)piperazine; tert-Butyl 4-(5-bromo-3-cyanopyridin-2-yl)piperazine-1-carboxylate; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-5-bromonicotinonitrile; 5-Bromo-2-(1-Boc-piperazin-4-yl)nicotinonitrile; 5-Bromo-3-cyano-2-(4-(N-Boc)piperazinyl)pyridine; BOC-5-Bromo-3-cyano-2-piperazinylpyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Bromo-3-Cyanopyridin-2-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.